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Science of Synthesis (Houben-Weyl) now MAC compatible

Posted on January 31, 2008

Science of Synthesis – a Web-based, authoritative information source on synthetic chemistry and methodology – is now available to UT Southwestern affiliates. Science of Synthesis is based on the book of the same name, the 5th edition of a famous text also known by the combined names of the authors of the first edition: Houben-Weyl.

Science of Synthesis provides critically evaluated methods for specific molecular transformations. The methods are organized by product class and currently available for organo-metallic and heterocyclic compounds. Each section includes an overview written by a field expert to provide an essential companion for the practicing synthetic chemist.

To access this resource, type "Science of Synthesis" in the search box on the Library's Web site. Acceptable browsers include Microsoft Internet Explorerer 5.5+ and Firefox 1.5+ (for Windows NT 4.0/95/98/2000/XP) as well as Safari 2.0+ (for MAC OS X). To use the built-in Java applet to submit structure/reaction searches, Java must be enabled on your system. Please note that Science of Synthesis requires disabling any pop-up blockers in Web browsers.

Science of Synthesis contains:

  • Review articles on general categories as well as specific product classes

  • Synthesis schemes and methods for molecular transformations

  • Experimental procedures for each methods

  • Efficient navigation within the resources

  • Structure and text searches for fast access to relevant examples

The database also provides access to the Houben-Weyl Methods of Organic Chemistry (4th edition), predecessor to Science of Synthesis and the reference series for preparative methods in organic chemistry. The Houben-Weyl 4th edition, and all earlier editions, are now available online as the "Houben-Weyl Archive" (1909 to 2004) and provide access to approximately 146,000 experimental procedures, 580,000 target compounds, and 700,000 references in all fields of synthetic organic chemistry dating back to the early 1800's.

Content in the Archive is accessible via links from every section of Science of Synthesis and can also be found directly through the online table of contents or by using the "text search" option.

Users may wish to review the Getting Started Manual for an introduction to Science of Synthesis and an explanation of its features. An online tutorial is also available.

The publisher's sales representative, Philip Heller, has also offered to assist UT researchers who have questions about the database. He can be reached by email at philip.heller@thieme.com. Mr. Heller can also arrange free group demonstrations via the Web, with participants using a toll-free number to dial in and to participate and ask questions via audio. The publisher also has a technical support desk reachable at help@thieme-chemistry.com.

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